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Which NMN Supplement Is The Best?

by: Editorial Team
September 25, 2023

As science and technology progress, there are more ways than ever to slow the signs of aging. One such method is to take anti-aging supplements like NMN. However, with so many NMN supplements available on the market, it can be challenging to narrow your selection down to one.

If you’re new to NMN supplements and want to get your money’s worth, this guide will help you choose the best product.

What Is NMN?

Nicotinamide mononucleotide (NMN) is a naturally-occurring molecule and direct precursor of nicotinamide adenine dinucleotide (NAD+). NAD+ controls hundreds of metabolic processes in the body, including transforming food into energy, delivering oxygen to the brain, and helping the muscles to recover.

However, for NMN to stimulate NAD+ production, it first has to enter cells in the body, which is not a simple process. NMN typically has to transform into nicotinamide riboside (NR), but the process slows as a person ages.

When NMN depletes, people become more at risk of developing age-related diseases.

The Benefits Of NMN Supplements

NMN supplementation can benefit you in the following ways:

Improve Brain Function

Taking NMN increases blood vessel dilation and oxygen flow to the brain, which enables the brain to carry out regular functions, such as memory retention and critical thinking.

Increase Metabolism

When you age, your metabolism slows, negatively impacting your endurance and the body’s ability to heal. According to an MIT study, animal subjects taking NMN demonstrated a 56% to 80% improvement in endurance after two months. NMN can also boost metabolic energy, making the supplement particularly popular amongst athletes.

Enhance Eye Health

As NAD+ levels drop, the eyes experience neurodegeneration and can even become subject to total vision loss. Fortunately, NMN protects the eye cells by reducing inflammation via DNA repair. It increases proteins in the eye, significantly enhancing tear production and keeping the eyes moistened.

Prevent Cardiac Disease

Mitochondrial dysfunction causes heart disease, a condition reversible through NMN treatment. Over time, NMN slows cell death and improves cardiac health by protecting the body’s mitochondrial ultrastructure.

Slow The Aging Process

When the body ages, it stops producing elastin, which keeps the skin smooth. In addition, the body develops more fat mass, leading to age-related weight gain. The good news is that NMN can reduce weight gain without suppressing the appetite as well as improve elastin and collagen production.

Restore Fertility

The older a woman becomes, the poorer the quality of oocytes in the body. You can increase the number and quality of maternal eggs through NMN, potentially restoring fertility.

Improved Insulin Sensitivity

NMN supplements enhance insulin sensitivity, allowing the blood to produce glucose more effectively. Blood sugar levels drop, making individuals more resistant to developing type 2 diabetes and obesity.

How To Compare NMN Supplements

All NAD+ boosters contain NMN, but no two supplements are exactly the same. Consider the following tips when choosing an NMN product that best suits your health requirements.

Visit Each Manufacturer’s Website

How a company advertises its products can say a lot about the products themselves. A good NMN supplier website should provide relevant and accurate information, including the following:

  • Product ingredients
  • How to use the product
  • NMN dose
  • Precautions
  • How to store the product

Note whether the manufacturer’s website has additional information in an FAQ section or live chat. As a consumer, you don’t want to spend too much time on a website to find the necessary information.

Compare Additives And Ingredients

Some manufacturers include other ingredients for supplementing NMN, such as mannitol or riboflavin. These ingredients increase the supplement’s bioavailability, allowing the skin to absorb it faster.

Alternatively, some manufacturers will use sublingual or liposomal NMN to enhance absorption.

Check For Third-Party Testing

Many supplements on the market aren’t FDA-regulated, allowing unverified companies in the supplement industry to make outlandish claims. If an NMN supplement seems too good to be true, don’t second guess – do your research.

The best NMN supplements are third-party tested with independent labs. Independent lab tests prove product quality and, more importantly, tell you when a company is mislabeling its product.

More importantly, be wary of companies that claim to have third-party testing but don’t post their results or certification. A reputable NMN brand is transparent about whether it uses pharmaceutical-grade ingredients verified by testing labs.

Read Customer Reviews

Customer reviews can be reliable sources for how effective a product is and whether it’s worth purchasing. Even if a customer review doesn’t rate a product perfectly, remember that different people can have vastly different experiences with supplements.

Weigh Out Price

The best NMN supplements don’t come cheap, but they shouldn’t also be outrageously priced. Most NMN supplementation costs about $70 or more for a bottle.

Similarly, you want to be wary of an NMN supplement that looks too cheap. You get what you pay for with a dirt-cheap NMN supplement.

Compare Product Purity

Only the best NMN supplements have a purity of 99%. In addition, an effective NMN supplement won’t contain filler ingredients like dairy, gluten, heavy metals, or artificial chemicals.

When comparing purity levels, ensure that a manufacturer tests the product directly instead of comparing it to other products. Just because one NMN supplement has a higher purity than another doesn’t mean it is 99% pure.

Pick The Right Form Of Delivery

NMN supplements are typically available in the following forms:

  • Sublingual delivery (liquid)
  • Powder form
  • Pill form
  • Lozenge form

Generally, sublingual NMN enters the bloodstream the fastest, quickly converting itself into NAD+. However, your choice of delivery will ultimately depend on your preferences. For instance, if you have trouble swallowing tablets and capsules, you might prefer to take NMN as a lozenge.

Some unique NMN capsules dissolve in water. However, you will have to store dissolved NMN in the fridge to maintain product stability.

Regardless of the type of NMN you take, it will absorb from the gut and into the bloodstream within two to three minutes. Tissue in the body should fully absorb the substance within 15 minutes.

Review Facility Procedures

How a manufacturer produces its NMN anti-aging supplements can dictate how safe and effective the product is. If a company doesn’t use a GMP-certified facility, there is no guarantee that its products are safe for human consumption.

When a manufacturer is GMP-certified, its employees and equipment are up to par with government standards. Some facilities might even be climate controlled to ensure product stability.

Different Types Of NMN Supplements

With so many NMN products on the market, picking the best NMN supplements is no easy choice. Use this guide to narrow your choices and select the right NMN supplements for your specific needs.

Pure NMN

Dosage: 100 g powder (take two level scoops of 500 mg daily, with or without food)


  • 50 servings of NMN powder
  • 1 g of NMN per serving
  • Vegan ingredients, no preservatives

Pure NMN powder is third-party lab-tested with a purity of 99% and 1% moisture. Its manufacturers implement Good Manufacturing Practices (GMP) and FDA-approved facilities that promise high-quality results.

Pure NMN products have been proven to sharpen cognitive skills by dilating the blood vessels and hastening blood flow to the brain. It slows cognitive decline and keeps you more alert and focused.

In addition, these supplements improve DNA repair processes, preventing damage and liver disease.

Renue By Science Sublingual Powder

Dosage: 250 mg sublingual (take two level scoops daily, with or without food)


  • 88 servings of NMN powder
  • 250 mg of NMN per scoop
  • Mannitol
  • Monk fruit
  • Citrus burst

Renue by Science’s sublingual NMN powder boasts enhanced bioavailability with improved absorption and transit through the small intestine. Its additives make the powder more palatable when taken sublingually and claim to make the product more efficient.

Its manufacturer uses an FDA-approved facility, third-party testing all its products. Renue by Scient also provides standard certifications for satisfaction guarantees.

However, not all Renue by Science NMN products have the same bioavailability. In addition, Renue by Science’s products are more expensive than most NMN competitors.

Forest Leaf

Dosage: 250 mg capsules (take 2 to 8 capsules daily depending on weight, with or without food)


  • 30 servings of NMN
  • Vegetable cellulose
  • Vegetable stearate
  • Silicon dioxide
  • Microcrystalline cellulose

If you have allergies, Forest Leaf is free of common allergens and appropriate for people with multiple health conditions. Its NMN capsules are soy-free and raise cellular NAD+ levels to repair DNA and prevent age-related dysfunctions. In addition, it helps to convert food into energy, enabling the body to burn fat and protein quickly.

However, Forest Leaf’s dosage is relatively small at only 250 mg per pill, which won’t absorb as quickly as sublingual administrations. Not to mention, Forest leaf’s third-party testing only reviews absorption rates – not purity.

ProHealth Longevity

Dosage: 1,000 mg capsules (take two capsules daily, with or without food)


  • 30 servings of NMN
  • Cellulose
  • Organic brown rice flour

ProHealth Longevity’s NMN supplements claim to provide superior anti-aging benefits, improved muscle health, and enhanced heart health. This NAD+ boosting supplement focuses delivery to the small intestine, which increases absorption by up to 100 times.

Unlike other NMN products, ProHealth’s capsules don’t contain any chemical solvents. Its development process is state-of-the-art, tapping overseas teams such as the Uthever Research and Development Team, Scientific Quality Standard Setting Team, and Production Management Team to satisfy global standards.

However, ProHealth supplements are on the pricier side and are only available online.

Wonderfeel Youngr

Dosage: 900 mg (take two capsules daily with a healthy fat source)


  • 30 servings of NMN
  • Ergothioneine
  • Trans-Resveratrol
  • Olea25
  • Vitamin D3
  • Cellulose
  • Maltodextrin
  • Organic rice hulls

Wonderfeel Youngr’s pharmaceutical-grade NMN supplements focus on age-related health benefits, including clarity, stabilized energy levels, and athletic performance. The company recommends taking its NMN capsules with healthy fat sources like yogurt or avocado to increase bioavailability and absorption.

Wonderfeel’s NMN products are excellent dietary supplements for individuals seeking internal and external results enhanced by additives like trans-resveratrol.

What gives Wonderfeel an edge is its clinical studies published online. Its results are promising and are spearheaded by Harvard scientist Andrew Salzman MD.

While Wonderfeel often scores five-star reviews, many claim its NMN supplementation is too expensive.

Double Wood NMN

Dosage: 250 mg (take 2 to 8 capsules a day)


  • 30 servings of NMN
  • Bovine gelatin
  • Organic rice flour

Double Wood provides a low NMN dose supplement that aims to improve the body’s vascular health, cellular health, and anti-aging abilities. In addition, Double Wood’s active ingredients are stabilized and don’t require refrigeration to stay fresh. Double Wood NMN supplements are all-natural and GMO-free.

However, they aren’t vegan-friendly. In addition, Double Wood NMN supplements aren’t appropriate for lactose-intolerant individuals. In addition, some have claimed to experience side effects like dizziness when taking Double Wood products.

Quicksilver Scientific

Dosage: 50 mg (take ½ teaspoon daily on an empty stomach)


  • Riboflavin
  • Vitamin B12
  • Proprietary blend (trimethylglycine, quercetin dihydrate, resveratrol)
  • Water
  • Glycerin
  • Ethanol
  • Phospholipids
  • Tocofersolan
  • Medium chain triglycerides
  • Natural citrus oils
  • Natural mixed tocopherols
  • Natural flavoring

Quicksilver Scientific’s NAD+ Platinum NMN is a liposomal NAD+ booster that mimics how the body transports NMN. Unlike most NMN supplements, Quicksilver Scientific combines its capsules with beneficial active ingredients like vitamin B12, which improves blood flow and cellular health.

Other ingredients like riboflavin provide anti-inflammatory, antioxidant, and anti-aging benefits. Because Quicksilver Scientific’s NMN product is liquid, it’ll absorb more quickly into the bloodstream than a pill.

The biggest downside of the Quicksilver Scientific NMN supplement is that its temperature-sensitive components must be refrigerated.

Pure NMN Extreme Potency By Nutriop Longevity

Dosage: 500 mg capsules (take two pills daily on an empty stomach)


  • 60 servings of NMN
  • Non-GMO HPMC

Nutriop Longevity has superior anti-aging and weight-loss attributes that improve cognitive function, boost metabolism, and enhance cellular health. Their high-quality NMN supplement is vegan and GMO-free. It’s also appropriate for individuals with allergies or who are lactose-intolerant.

While Nutriop Longevity’s NMN tablets have received ample praise, they are on the pricier side and don’t come with a money-back guarantee.

Approved Science NMN + Bioperine

Dosage: 500 mg (take two capsules daily before meals)


  • Rice flour
  • Vegetable cellulose
  • Magnesium stearate
  • Silicon dioxide

Approved Science’s NMN formula is unique because it contains Bioperine, which increases bioavailability. Plus, Approved Science boasts a fully patented version of nicotinamide mononucleotide supplements, making it among the most stable on the market.

This trusted longevity supplement brand facilitates regular third-party testing and gives customers a 100% money-back guarantee. Plus, its superior stability means the product doesn’t have to be refrigerated.

Unfortunately, shipping from Approved Science is not free.

The Bottom Line

While the science is relatively young, nicotinamide mononucleotide (NMN) has been proven to promote healthy aging, improve cardiovascular health, and enhance the immune system better than other supplements. However, choosing the right product can be challenging, especially because there are hundreds on the market.

If you’re looking for the best NMN supplement for people of all ages, Pure NMN provides superior long-term health benefits.

Frequently Asked Questions About NMN Supplements

What is the best NMN supplement?

The best NMN supplement should be 99% pure, have no filler ingredients, and be third-party lab-tested. We recommend taking Pure NMN, a cost-effective, healthy aging supplement that naturally increases your NAD+ levels over time.

Are there ways to make NMN more effective?

You can boost the anti-aging effects of NMN with natural food sources. However, foods like broccoli, tomato, mushroom, and cabbage can enhance the effects of NMN.

Is it necessary to take NMN?

While taking NMN isn’t necessary or essential, it is highly recommended for individuals who want to boost their energy, improve heart health, and take advantage of its anti-aging properties. Always seek professional medical advice before introducing NMN into your daily routine.

What is the best form of NMN?

The best form of NMN will ultimately depend on your needs and preferences. That said, sublingual powder or liquid typically absorbs into the bloodstream fastest.

What time should you take NMN, so it’s most effective?

The best time to take NMN is in the morning because of its ability to regulate circadian rhythms. In addition, the body’s NAD+ levels are also highest in the morning.

Where can you buy NMN supplements?

You can buy safe supplements from manufacturers with FDA-approved labs. Reputable brands will also have GMP certification and accurate information regarding their products.

Is the best-quality NMN expensive?

Most high-quality NMN products are at least $70 a bottle, though some can cost as much as $100 or more. Beware of products that seem too cheap – they may contain filler ingredients and may not provide the anti-aging effects you need.

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